SPS1 rabbit pAb
Ucallm_WP4330-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010],
Specifications
| Size | 50μL/100μL |
| Target | SPS1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 43kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SPS1 AA range: 323-373 |
| Specificity | This antibody detects endogenous levels of SPS1 at Human/Mouse |
| Gene Name | SEPHS1 SELD SPS SPS1 |
| Protein Name | SPS1 |
| Other Name | |
| Species | Human |
| Gene ID | 22929 |
| Uniprot | P49903, |
| Species.1 | Mouse |
| Gene ID.1 | 109079 |
| Uniprot.1 | Q8BH69 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Peripheral membrane protein . Nucleus membrane; Peripheral membrane protein .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm . |
| Tissue Expression | [Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases.; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases.; [Isoform 3]: Gradually expressed during the cell cycle until S phase and then decreases. |
| Signaling_pathway | |
| Research Areas | >>Selenocompound metabolism; / >>Metabolic pathways |
| Function | Catalytic activity:ATP + selenide + H(2)O = AMP + selenophosphate + phosphate.,Caution:The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is proven, it is possible Cys-31 is the active site.,Function:Synthesizes selenophosphate from selenide and ATP.,similarity:Belongs to the selenophosphate synthetase 1 family. Class II subfamily., |
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