Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SPSB3 AA range: 102-152
Specificity
This antibody detects endogenous levels of SPSB3 at Human/Mouse
Gene Name
SPSB3 C16orf31 SSB3
Protein Name
SPSB3
Other Name
SPRY domain-containing SOCS box protein 3; / SSB-3
Species
Human
Gene ID
90864
Uniprot
Q6PJ21,
Species.1
Mouse
Gene ID.1
79043
Uniprot.1
Q571F5
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
intracellular,
Tissue Expression
Brain,Eye,Hypothalamus,Testis,
Signaling_pathway
Research Areas
Function
Domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,Function:May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,sequence Caution:Intron retention.,similarity:Belongs to the SPSB family.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 SOCS box domain.,subunit:Interacts with MET.,