SKU: WP14566 Categories: ,

SR-1F Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14566-100
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Product details

Background:

function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity., similarity:Belongs to the G-protein coupled receptor 1 family.,

Specifications

Size50μL/100μL
TargetSR-1F
ReactivityHuman, Mouse, Rat, Monkey
ApplicationsWB, ELISA, IHC
MW(Calculated)
MW(Observed)38kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human 5-HT-1F. AA range:101-150
SpecificitySR-1F Polyclonal Antibody detects endogenous levels of SR-1F protein.
Gene NameHTR1F
Protein Name5-hydroxytryptamine receptor 1F
Other NameHTR1F; / HTR1EL; / 5-hydroxytryptamine receptor 1F; / 5-HT-1F; / 5-HT1F; / Serotonin receptor 1F
SpeciesHuman
Gene ID3355
UniprotP30939,
Species.1Mouse
Gene ID.115557
Uniprot.1Q02284,
Species.2Rat
Gene ID.2
Uniprot.2P30940
Cellular LocalizationCell membrane; Multi-pass membrane protein .
Tissue ExpressionBrain,
Signaling_pathwayEnvironmental Information Processing >> Signal transduction >> cAMP signaling pathway
Research Areas>>cAMP signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Serotonergic synapse; / >>Taste transduction
FunctionFunction:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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