SKU: WP14573 Categories: ,

SR-5A Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14573-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetSR-5A
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)36kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64
SpecificitySR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein.
Gene NameHTR5A
Protein Name5-hydroxytryptamine receptor 5A
Other NameHTR5A; / 5-hydroxytryptamine receptor 5A; / 5-HT-5; / 5-HT-5A; / 5-HT5A; / Serotonin receptor 5A
SpeciesHuman
Gene ID3361
UniprotP47898,
Species.1Mouse
Gene ID.1
Uniprot.1P30966
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue ExpressionBrain,Cerebellum,
Signaling_pathwayEnvironmental Information Processing >> Signal transduction >> Calcium signaling pathway
Research Areas>>Calcium signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Serotonergic synapse
FunctionFunction:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Please login to post questions
Back to Top
Product has been added to your cart