Product details
Background:
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SRP68 rabbit pAb
Ucallm_WP6265-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SRP68 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 69kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SRP68 |
| Specificity | This antibody detects endogenous levels of SRP68 at Human, Mouse |
| Gene Name | SRP68 |
| Protein Name | Signal recognition particle 68 kDa protein (SRP68) |
| Other Name | |
| Species | Human |
| Gene ID | 6730 |
| Uniprot | Q9UHB9, |
| Species.1 | Mouse |
| Gene ID.1 | 217337 |
| Uniprot.1 | Q8BMA6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus, nucleolus . Endoplasmic reticulum . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) . The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER . The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER . Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently . The SRP complex possibly participates in the elongation arrest function (By similarity). |
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