Price range: $268.00 through $328.00
Background:
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | STEAP1 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human STEAP1. AA range:31-80 |
| Specificity | STEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein. |
| Gene Name | STEAP1 |
| Protein Name | Metalloreductase STEAP1 |
| Other Name | STEAP1; / PRSS24; / STEAP; / Metalloreductase STEAP1; / Six-transmembrane epithelial antigen of prostate 1 |
| Species | Human |
| Gene ID | 26872 |
| Uniprot | Q9UHE8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9CWR7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endosome membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitously expressed. Highly expressed in prostate tumors. |
| Signaling_pathway | |
| Research Areas | >>Mineral absorption |
| Function | cofactor:FAD.,Function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitously expressed. Highly expressed in prostate tumors., |
