Symmetric Di-Methyl Arginine Specific Antibody Conjugated Agarose Beads
Ucallm_WT9159B-100
$999.00
Product details
Symmetric Di-Methyl Arginine Specific Antibody Conjugated Agarose Beads is an immunoaffinity enrichment tool for symmetric dimethyl arginine (SDMA) peptides in mass spectrometry-based proteomics. The highly specific antibody selectively captures target modified peptides without cross-reactivity, is applicable to all species, efficiently enriches low-abundance peptides and reduces background interference, delivering stable and reliable results for symmetric dimethyl arginine modification research.
Specifications
| Target | Symmetric Di-Methyl Arginine |
| Reactivity | Species Independent |
| Application | IAC, IAP, IP |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | |
| Conjugate | Agarose Beads |
| Modification | Symmetric Dimethylation of Arginine |
| Modified site | Arg (R) |
| Recommended dilution ratio | |
| Composition | |
| Purification process | Protein A |
| Purity | |
| Storage | 50% slurry in PBS pH7.4, 0.05% Proclin 300. Ensure thorough mixing before each use. Wide-mouth pipette tips are recommended. In case of difficulty in aspiration due to improper operation, additional Storage Buffer can be added at your discretion. |
| Stability | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
| Clonal | Recombinant monoclonal |
| Clone Number | |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein Name | |
| Alternative name | Rme2 (sy) |
| Organism-1 | |
| GeneID-1 | |
| SwissProt-1 | |
| Organism-2 | |
| GeneID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| GeneID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Background | Histones and non-histone proteins are subjected to a variety of enzyme-catalyzed post-translational modifications, including acetylation, methylation, phosphorylation and ubiquitination. Symmetric dimethyl arginine (SDMA) is an important arginine methylation mark catalyzed primarily by type II protein arginine methyltransferases. It is widely distributed in eukaryotic cells and abundantly present in chromatin proteins, RNA-binding factors and signal transduction molecules. SDMA participates in the regulation of chromatin remodeling, gene transcription, RNA splicing, DNA damage response and cell fate determination. Dysregulation of symmetric arginine dimethylation is closely linked to inflammation, tumorigenesis, cardiovascular disorders and neurodegenerative diseases, serving as a critical epigenetic marker for biological mechanism research and disease pathological study. |
| Cellular Localization |
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