SKU: WP14635 Categories: ,

Synaptotagmin X Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14635-100
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Product details

Background:

cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains., function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis., similarity:Belongs to the synaptotagmin family., similarity:Contains 2 C2 domains., subunit:Homodimer. Can also form heterodimers., tissue specificity:Expressed only in pancreas, lung and kidney.,

Specifications

Size50μL/100μL
TargetSynaptotagmin X
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC
MW(Calculated)
MW(Observed)55kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from Synaptotagmin X . at AA range: 380-460
SpecificitySynaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein.
Gene NameSYT10
Protein NameSynaptotagmin-10
Other NameSYT10; / Synaptotagmin-10; / Synaptotagmin X; / SytX
SpeciesHuman
Gene ID341359
UniprotQ6XYQ8,
Species.1Mouse
Gene ID.154526
Uniprot.1Q9R0N4,
Species.2Rat
Gene ID.260567
Uniprot.2O08625
Cellular LocalizationCytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .
Tissue ExpressionExpressed only in pancreas, lung and kidney.
Signaling_pathway
Research Areas
Functioncofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,Function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
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