Synaptotagmin X Polyclonal Antibody
Product details
Background:
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains., function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis., similarity:Belongs to the synaptotagmin family., similarity:Contains 2 C2 domains., subunit:Homodimer. Can also form heterodimers., tissue specificity:Expressed only in pancreas, lung and kidney.,
Specifications
| Size | 50μL/100μL |
| Target | Synaptotagmin X |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | |
| MW(Observed) | 55kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460 |
| Specificity | Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein. |
| Gene Name | SYT10 |
| Protein Name | Synaptotagmin-10 |
| Other Name | SYT10; / Synaptotagmin-10; / Synaptotagmin X; / SytX |
| Species | Human |
| Gene ID | 341359 |
| Uniprot | Q6XYQ8, |
| Species.1 | Mouse |
| Gene ID.1 | 54526 |
| Uniprot.1 | Q9R0N4, |
| Species.2 | Rat |
| Gene ID.2 | 60567 |
| Uniprot.2 | O08625 |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. . |
| Tissue Expression | Expressed only in pancreas, lung and kidney. |
| Signaling_pathway | |
| Research Areas | |
| Function | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,Function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney., |
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