Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human Syntaxin 1A/Syntaxin 1B
Specificity
This antibody detects endogenous levels of Syntaxin 1A/Syntaxin 1B at Human, Mouse,Rat
Gene Name
STX1B STX1B1 STX1B2
Protein Name
Syntaxin-1B (Syntaxin-1B1) (Syntaxin-1B2)
Other Name
Species
Human
Gene ID
112755
Uniprot
P61266,
Species.1
Mouse
Gene ID.1
56216
Uniprot.1
P61264,
Species.2
Rat
Gene ID.2
24923
Uniprot.2
P61265
Cellular Localization
[Isoform 1]: Membrane; Single-pass type IV membrane protein .; [Isoform 2]: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Colocalizes with Lamin A/C and NuMA in interphasic nuclei, and with NuMA and gamma-tubulin in the pericentrosomal region of the mitotic spindle in dividing cells.
Tissue Expression
Signaling_pathway
Organismal Systems >> Nervous system >> Synaptic vesicle cycle
Research Areas
Function
Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity).