Product details
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Syntaxin 4 rabbit pAb
Ucallm_WP6230-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | STX4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 33kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Syntaxin 4 |
| Specificity | This antibody detects endogenous levels of Syntaxin 4 at Human, Mouse,Rat |
| Gene Name | STX4 STX4A |
| Protein Name | Syntaxin-4 (Renal carcinoma antigen NY-REN-31) |
| Other Name | |
| Species | Human |
| Gene ID | 6810 |
| Uniprot | Q12846, |
| Species.1 | Mouse |
| Gene ID.1 | 20909 |
| Uniprot.1 | P70452, |
| Species.2 | Rat |
| Gene ID.2 | 81803 |
| Uniprot.2 | Q08850 |
| Cellular Localization | Cell membrane; Single-pass type IV membrane protein . Cell projection, neuron projection . Localizes to neurite tips in neuronal cells. . |
| Tissue Expression | Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation. |
| Signaling_pathway | |
| Research Areas | |
| Function | Plasma membrane t-SNARE that mediates docking of transport vesicles (By similarity). Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity). In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity). Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity). |
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