SKU: WP1809 Categories: ,

SYT4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1809-100
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Product details

Background:

cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains., function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis., similarity:Belongs to the synaptotagmin family., similarity:Contains 2 C2 domains., tissue specificity:Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.,

Specifications

Size50μL/100μL
TargetSYT4
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)46kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificitySYT4 Polyclonal Antibody detects endogenous levels of protein.
Gene NameSYT4 KIAA1342
Protein NameSynaptotagmin-4 (Synaptotagmin IV) (SytIV)
Other Name
SpeciesHuman
Gene ID6860
UniprotQ9H2B2,
Species.1Mouse
Gene ID.1
Uniprot.1P40749,
Species.2Rat
Gene ID.2
Uniprot.2P50232
Cellular LocalizationCytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane; Single-pass membrane protein .
Tissue ExpressionExpressed in melanocytes (PubMed:23999003). Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus (PubMed:23999003).
Signaling_pathway
Research Areas
Functioncofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,Function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,tissue specificity:Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus.,
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