SYT8 Polyclonal Antibody
Ucallm_WP1812-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
Specifications
| Size | 50μL/100μL |
| Target | SYT8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 44kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SYT8 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SYT8 |
| Protein Name | Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII) |
| Other Name | |
| Species | Human |
| Gene ID | 90019 |
| Uniprot | Q8NBV8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9R0N6, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q925B4 |
| Cellular Localization | Cell membrane; Single-pass type III membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome . |
| Tissue Expression | Lung,Placenta,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Not known. As it is truncated compared to orthologs, its function is not obvious.,sequence Caution:The sequence differs from that shown because it is a pre-mRNA.,similarity:Belongs to the synaptotagmin family., |
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