Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human T2FA AA range: 462-512
Specificity
This antibody detects endogenous levels of T2FA at Human/Mouse/Rat
Gene Name
GTF2F1 RAP74
Protein Name
T2FA
Other Name
Species
Human
Gene ID
2962
Uniprot
P35269,
Species.1
Mouse
Gene ID.1
98053
Uniprot.1
Q3THK3,
Species.2
Rat
Gene ID.2
316123
Uniprot.2
Q6AY96
Cellular Localization
Nucleus.
Tissue Expression
Signaling_pathway
Research Areas
>>Basal transcription factors
Function
Caution:Was reported (PubMed:10428810) to have a protein kinase activity and to autophosphorylates on Ser-385 and Thr-389.,Function:TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.,PTM:Phosphorylated on Ser and other residues by TAF1 and casein kinase II-like kinases.,similarity:Belongs to the TFIIF alpha subunit family.,subunit:Heterodimer of an alpha and a beta subunit. Interacts with GTF2F2 and CTDP1. Interacts with TAF6/TAFII80.,