Product details
Background:
T2H2L rabbit pAb
Ucallm_WP16207-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | T2H2L |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 43kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human T2H2L AA range: 275-325 |
| Specificity | This antibody detects endogenous levels of T2H2L at Human |
| Gene Name | GTF2H2C; GTF2H2D |
| Protein Name | T2H2L |
| Other Name | |
| Species | Human |
| Gene ID | 728340 |
| Uniprot | Q6P1K8 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Basal transcription factors; / >>Nucleotide excision repair; / >>Viral carcinogenesis |
| Function | Alternative products:A number of isoforms may be produced. The isoforms may be also produced by incomplete gene duplication,Function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,Function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.,similarity:Belongs to the GTF2H2 family.,similarity:Contains 1 VWFA domain.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with XPB, XPD, GTF2H1 and GTF2H3.,tissue specificity:Widely expressed, with higher expression in skeletal muscle., |
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