SKU: WP8467 Categories: ,

TAF1C rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8467-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTAF1C
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)96kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TAF1C
SpecificityThis antibody detects endogenous levels of TAF1C at Human, Mouse,Rat
Gene NameTAF1C
Protein NameTATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)
Other Name
SpeciesHuman
Gene ID9013
UniprotQ15572,
Species.1Mouse
Gene ID.121341
Uniprot.1Q6PDZ2,
Species.2Rat
Gene ID.2361420
Uniprot.2Q6P773
Cellular LocalizationNucleus.
Tissue Expression
Signaling_pathway
Research Areas
FunctionComponent of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
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