TAF1C rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TAF1C |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 96kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TAF1C |
| Specificity | This antibody detects endogenous levels of TAF1C at Human, Mouse,Rat |
| Gene Name | TAF1C |
| Protein Name | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) |
| Other Name | |
| Species | Human |
| Gene ID | 9013 |
| Uniprot | Q15572, |
| Species.1 | Mouse |
| Gene ID.1 | 21341 |
| Uniprot.1 | Q6PDZ2, |
| Species.2 | Rat |
| Gene ID.2 | 361420 |
| Uniprot.2 | Q6P773 |
| Cellular Localization | Nucleus. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
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