Price range: $268.00 through $328.00
Background:
potassium two pore domain channel subfamily K member 15(KCNK15) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | TASK-5 |
| Reactivity | Human, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 42kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KCNK15. AA range:273-322 |
| Specificity | TASK-5 Polyclonal Antibody detects endogenous levels of TASK-5 protein. |
| Gene Name | KCNK15 |
| Protein Name | Potassium channel subfamily K member 15 |
| Other Name | KCNK15; / TASK5; / Potassium channel subfamily K member 15; / Acid-sensitive potassium channel protein TASK-5; / TWIK-related acid-sensitive K; / +; / channel 5; / Two pore potassium channel KT3.3; / Two pore K; / +; / channel KT3.3 |
| Species | Human |
| Gene ID | 60598 |
| Uniprot | Q9H427 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Expression | Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.,polymorphism:Three variant polypeptides are known: TASK-5A, TASK-5B and TASK-5C. The sequence shown is that of TASK-5C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Heterodimer .,tissue specificity:Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland., |
