Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TAX1BP1
Specificity
This antibody detects endogenous levels of TAX1BP1 at Human, Mouse,Rat
Gene Name
TAX1BP1 T6BP PRO0105
Protein Name
Tax1-binding protein 1 (TRAF6-binding protein)
Other Name
Species
Human
Gene ID
8887
Uniprot
Q86VP1,
Species.1
Mouse
Gene ID.1
52440
Uniprot.1
Q3UKC1,
Species.2
Rat
Gene ID.2
246244
Uniprot.2
Q66HA4
Cellular Localization
Tissue Expression
Expressed in all tissues tested.
Signaling_pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal;Cellular Processes >> Transport and catabolism >> Mitophagy - animal
Research Areas
Function
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade.