TB10B Polyclonal Antibody
Ucallm_WP2045-50
Price range: $268.00 through $328.00
Product details
Background:
TBC1 domain family member 10B(TBC1D10B) Homo sapiens Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010],
Specifications
| Size | 50μL/100μL |
| Target | TB10B |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 88kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TB10B Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TBC1D10B FP2461 |
| Protein Name | TBC1 domain family member 10B (Rab27A-GAP-beta) |
| Other Name | |
| Species | Human |
| Gene ID | 26000 |
| Uniprot | Q4KMP7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BHL3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . In melanocytes, located at the periphery of cells. |
| Tissue Expression | Brain,Epithelium,Ovary,Placenta,PNS,Teratocarcinoma,Testis,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May act as a GTPase-activating protein.,similarity:Contains 1 Rab-GAP TBC domain., |
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