Product details
Background:
TBRG1 rabbit pAb
Ucallm_WP8265-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TBRG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 45kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TBRG1 |
| Specificity | This antibody detects endogenous levels of TBRG1 at Human, Mouse,Rat |
| Gene Name | TBRG1 NIAM |
| Protein Name | Transforming growth factor beta regulator 1 (Nuclear interactor of ARF and Mdm2) |
| Other Name | |
| Species | Human |
| Gene ID | 84897 |
| Uniprot | Q3YBR2, |
| Species.1 | Mouse |
| Gene ID.1 | 21376 |
| Uniprot.1 | Q3UB74, |
| Species.2 | Rat |
| Gene ID.2 | 300521 |
| Uniprot.2 | Q5PQK8 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma. |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. |
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