SKU: WP14696 Categories: ,

TBX15/18 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14696-100
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Product details

Background:

T-box 18(TBX18) Homo sapiens This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012],

Specifications

Size50μL/100μL
TargetTBX15/18
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)64kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human TBX15/18. AA range:161-210
SpecificityTBX15/18 Polyclonal Antibody detects endogenous levels of TBX15/18 protein.
Gene NameTBX15/TBX18
Protein NameT-box transcription factor TBX15/18
Other NameTBX18; / T-box transcription factor TBX18; / T-box protein 18; / TBX15; / TBX14; / T-box transcription factor TBX15; / T-box protein 15; / T-box transcription factor TBX14; / T-box protein 14
SpeciesHuman
Gene ID9096
UniprotO95935;Q96SF7,
Species.1Mouse
Gene ID.176365;21384
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionLung,
Signaling_pathway
Research Areas
FunctionFunction:Probable transcriptional regulator involved in developmental processes.,similarity:Contains 1 T-box DNA-binding domain.,
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