SKU: WP14698 Categories: ,

TBX2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14698-100
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Product details

Background:

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetTBX2
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)74kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human TBX2. AA range:251-300
SpecificityTBX2 Polyclonal Antibody detects endogenous levels of TBX2 protein.
Gene NameTBX2
Protein NameT-box transcription factor TBX2
Other NameTBX2; / T-box transcription factor TBX2; / T-box protein 2
SpeciesHuman
Gene ID6909
UniprotQ13207,
Species.1Mouse
Gene ID.121385
Uniprot.1Q60707
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionExpressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.
Signaling_pathway
Research Areas
FunctionFunction:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.,
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