Product details
Background:
TDRD3 rabbit pAb
Ucallm_WP7574-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TDRD3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 72kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TDRD3 |
| Specificity | This antibody detects endogenous levels of TDRD3 at Human, Mouse,Rat |
| Gene Name | TDRD3 |
| Protein Name | Tudor domain-containing protein 3 |
| Other Name | |
| Species | Human |
| Gene ID | 81550 |
| Uniprot | Q9H7E2, |
| Species.1 | Mouse |
| Gene ID.1 | 219249 |
| Uniprot.1 | Q91W18, |
| Species.2 | Rat |
| Gene ID.2 | 306066 |
| Uniprot.2 | Q66HC1 |
| Cellular Localization | Cytoplasm . Nucleus . Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules. . |
| Tissue Expression | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Signaling_pathway | |
| Research Areas | |
| Function | Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. |
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