TDRD5 rabbit pAb
Ucallm_WP8129-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TDRD5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 108kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TDRD5 |
| Specificity | This antibody detects endogenous levels of TDRD5 at Human, Mouse,Rat |
| Gene Name | TDRD5 |
| Protein Name | Tudor domain-containing protein 5 |
| Other Name | |
| Species | Human |
| Gene ID | 163589 |
| Uniprot | Q8NAT2, |
| Species.1 | Mouse |
| Gene ID.1 | 214575 |
| Uniprot.1 | Q5VCS6, |
| Species.2 | Rat |
| Gene ID.2 | 289129 |
| Uniprot.2 | B4F7C4 |
| Cellular Localization | Cytoplasm . Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). |
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