Product details
Background:
- Please choose product options by visiting TMEM175 rabbit pAb.
- Please choose product options by visiting U-Blot® Human BAG3 Antibody , FITC.
- Please choose product options by visiting Rabbit anti Human IgG+IgM+IgA - AMCA.
THAP1 rabbit pAb
Ucallm_WP6108-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | THAP1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 23kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human THAP1 |
| Specificity | This antibody detects endogenous levels of THAP1 at Human, Mouse,Rat |
| Gene Name | THAP1 |
| Protein Name | THAP domain-containing protein 1 |
| Other Name | |
| Species | Human |
| Gene ID | 55145 |
| Uniprot | Q9NVV9, |
| Species.1 | Mouse |
| Gene ID.1 | 73754 |
| Uniprot.1 | Q8CHW1, |
| Species.2 | Rat |
| Gene ID.2 | 306547 |
| Uniprot.2 | Q5U208 |
| Cellular Localization | Nucleus, nucleoplasm . Nucleus, PML body . |
| Tissue Expression | Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. |
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