Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side .
Tissue Expression
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
Signaling_pathway
Research Areas
Function
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.