Product details
Background:
TIPIN rabbit pAb
Ucallm_WP8608-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TIPIN |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 33kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TIPIN |
| Specificity | This antibody detects endogenous levels of TIPIN at Human, Mouse,Rat |
| Gene Name | TIPIN |
| Protein Name | TIMELESS-interacting protein |
| Other Name | |
| Species | Human |
| Gene ID | 54962 |
| Uniprot | Q9BVW5, |
| Species.1 | Mouse |
| Gene ID.1 | 66131 |
| Uniprot.1 | Q91WA1, |
| Species.2 | Rat |
| Gene ID.2 | 363076 |
| Uniprot.2 | Q4QR88 |
| Cellular Localization | Cytoplasm . Nucleus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. |
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