U-Blot® TMEM161B Rabbit mAb
WR4736 Western Blot analysis using A549 lysates,primary antibody was diluted at 1:1000, 4°over night, Dylight 800 secondary antibody(WS0446)was diluted at 1:10000, 37° 1hour.
Price range: $268.00 through $328.00
Product details
Background:Enables ATPase binding activity. Involved in dendrite morphogenesis and lysosome localization. Located in endosome and lysosomal membrane. Implicated in hypomyelinating leukodystrophy 16. [provided by Alliance of Genome Resources, Apr 2025]
Specifications
| Size | 50μL/100μL |
| Target | TMEM161B |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 54kD |
| MW(Observed) | 54kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-1:5000; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1096R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | TMEM161B,UNQ679/PRO1313 |
| Protein Name | Transmembrane protein 161B |
| Other Name | |
| Species | Human |
| Gene ID | 153396 |
| Uniprot | Q8NDZ6, |
| Species.1 | Mouse |
| Gene ID.1 | 71900 |
| Uniprot.1 | Q80X71 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7SY10}; Multi-pass membrane protein {ECO:0000255}. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | FUNCTION: Essential for maintaining normal cardiac rhythm in the developing heart and for neonatal survival (By similarity). Inhibits potassium and calcium currents in the cardiomyocytes, this assists in timely action potential repolarization and thereby maintains normal cardiac rhythm (By similarity). {ECO:0000250|UniProtKB:Q8C2L6}. |
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