TMEM25 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TMEM25 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 40kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TMEM25 |
| Specificity | This antibody detects endogenous levels of TMEM25 at Human, Mouse |
| Gene Name | TMEM25 UNQ2531/PRO6030 |
| Protein Name | Transmembrane protein 25 |
| Other Name | |
| Species | Human |
| Gene ID | 84866 |
| Uniprot | Q86YD3, |
| Species.1 | Mouse |
| Gene ID.1 | 71687 |
| Uniprot.1 | Q9DCF1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane; Single-pass type I membrane protein .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; Late endosome . Lysosome . |
| Tissue Expression | Expressed throughout the brain with higher levels in the pyramidal cell layer of the hippocampal CA1 and CA3 regions. Also highly expressed within the hippocampal dentate gyrus region and cerebellum and in scattered neurons in the cerebral cortex. |
| Signaling_pathway | |
| Research Areas | |
| Function | In neurons, modulates the degradation of NMDA receptor GRIN2B subunit. Plays a role in the regulation of neuronal excitability. |
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