Product details
Background:
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TRIM26 rabbit pAb
Ucallm_WP7624-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TRIM26 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 59kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TRIM26 |
| Specificity | This antibody detects endogenous levels of TRIM26 at Human, Mouse,Rat |
| Gene Name | TRIM26 RNF95 ZNF173 |
| Protein Name | Tripartite motif-containing protein 26 (Acid finger protein) (AFP) (RING finger protein 95) (Zinc finger protein 173) |
| Other Name | |
| Species | Human |
| Gene ID | 7726 |
| Uniprot | Q12899, |
| Species.1 | Mouse |
| Gene ID.1 | 22670 |
| Uniprot.1 | Q99PN3, |
| Species.2 | Rat |
| Gene ID.2 | 309586 |
| Uniprot.2 | P62603 |
| Cellular Localization | Cytoplasm . Nucleus . Viral infection mediates TRIM26 nuclear translocation. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1. |
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