TrpRS rabbit pAb
Ucallm_WP7152-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | WARS1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 52kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TrpRS |
| Specificity | This antibody detects endogenous levels of TrpRS at Human, Mouse,Rat |
| Gene Name | WARS IFI53 WRS |
| Protein Name | Tryptophan--tRNA ligase, cytoplasmic (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS] |
| Other Name | |
| Species | Human |
| Gene ID | 7453 |
| Uniprot | P23381, |
| Species.1 | Mouse |
| Gene ID.1 | 22375 |
| Uniprot.1 | P32921, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q6P7B0 |
| Cellular Localization | Cytoplasm. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. |
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