Product details
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TRUB2 rabbit pAb
Ucallm_WP7312-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TRUB2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 36kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TRUB2 |
| Specificity | This antibody detects endogenous levels of TRUB2 at Human, Mouse,Rat |
| Gene Name | TRUB2 |
| Protein Name | Probable tRNA pseudouridine synthase 2 (EC 5.4.99.-) |
| Other Name | |
| Species | Human |
| Gene ID | 26995 |
| Uniprot | O95900, |
| Species.1 | Mouse |
| Gene ID.1 | 227682 |
| Uniprot.1 | Q91WG3, |
| Species.2 | Rat |
| Gene ID.2 | 366012 |
| Uniprot.2 | Q5XFW2 |
| Cellular Localization | Mitochondrion matrix . Localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs . As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation . Also catalyzes pseudouridylation of some tRNAs, including synthesis of pseudouridine(55) from uracil-55, in the psi GC loop of a subset of tRNAs . |
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