TSG10 rabbit pAb
Ucallm_WP4539-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TSG10 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 77kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TSG10 AA range: 412-462 |
| Specificity | This antibody detects endogenous levels of TSG10 at Human/Mouse/Rat |
| Gene Name | TSGA10 CEP4L |
| Protein Name | TSG10 |
| Other Name | |
| Species | Human |
| Gene ID | 80705 |
| Uniprot | Q9BZW7, |
| Species.1 | Mouse |
| Gene ID.1 | 211484 |
| Uniprot.1 | Q6NY15, |
| Species.2 | Rat |
| Gene ID.2 | 252923 |
| Uniprot.2 | Q9Z220 |
| Cellular Localization | Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). . |
| Tissue Expression | Expressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May play a role in the sperm tail fibrous sheath, a major sperm tail structure.,PTM:Appears to be processed in a 27 kDa and a 55 kDa peptide containing respectively the N-terminal and the C-terminal part of the precursor.,similarity:Belongs to the CEP135/TSGA10 family.,subcellular location:The 27 kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail while the 55 kDa peptide localizes to the midpiece.,tissue specificity:Testis specific., |
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