SKU: WP17704 Categories: ,

TSLP rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17704-100
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Product details

Background:

function:Cytokine that induces the release of T cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells., induction:Released by primary epithelial cells in response to certain microbial products, physical injury, or inflammatory cytokines., subunit:Interacts with a receptor composed of CRLF2 and IL7R., tissue specificity:Expressed in a number of tissues including heart, liver and prostate.,

Specifications

Size50μL/100μL
TargetTSLP
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)17kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:1000-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TSLP AA range: 91-140
SpecificityThis antibody detects endogenous levels of Human TSLP
Gene NameTSLP
Protein NameTSLP
Other NameThymic stromal lymphopoietin
SpeciesHuman
Gene ID85480
UniprotQ969D9,
Species.1Mouse
Gene ID.153603
Uniprot.1Q9JIE6
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted .
Tissue ExpressionIsoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva.
Signaling_pathwayEnvironmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas>>Cytokine-cytokine receptor interaction; / >>JAK-STAT signaling pathway
Function
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