TSSP rabbit pAb
Product details
Background:
This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | TSSP |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 57kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TSSP AA range: 50-100 |
| Specificity | This antibody detects endogenous levels of TSSP at Human/Mouse |
| Gene Name | PRSS16 TSSP |
| Protein Name | TSSP |
| Other Name | |
| Species | Human |
| Gene ID | 10279 |
| Uniprot | Q9NQE7, |
| Species.1 | Mouse |
| Gene ID.1 | 54373 |
| Uniprot.1 | Q9QXE5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic vesicle. Vesicular, either lysosomal or endosomal. |
| Tissue Expression | Expressed predominantly in cortical thymic epithelial cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed in fetal thymus.,Function:Protease that may play a role in T-cell development.,similarity:Belongs to the peptidase S28 family.,subcellular location:Vesicular, either lysosomal or endosomal.,tissue specificity:Expressed predominantly in cortical thymic epithelial cells., |
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