SKU: WM1278 Categories: ,

Tubulin γ [PT2188] mouse mAb

Price range: $268.00 through $328.00

SKU: WM1278-50
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Product details

Background:
tubulin gamma 1(TUBG1) Homo sapiens This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],

Specifications

TargetTubulin γ
ReactivityHuman
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)48kD
Host SpeciesMouse
IsotypeIgG2b,Kappa
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityMonoclonal
Clone NumberPT2188
ImmunogenSynthesized peptide derived from human Tubulin γ. AA range: 350-451
Sequence
SpecificityThis antibody detects endogenous levels of Tubulin γ protein.
Gene NameTUBG1 TUBG
Protein NameTubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
Other NameTubulin gamma-1 chain; / Gamma-1-tubulin; / Gamma-tubulin complex component 1; / GCP-1
SpeciesHuman
Gene ID-17283
UniprotP23258;Q9NRH3,
Species.1Mouse
Gene ID-2103733
Uniprot.1P83887,
Species.2Rat
Gene ID-3252921
Uniprot.2P83888
Organism-4
Gene ID-4
SwissProt-4
Backgroundtubulin gamma 1(TUBG1) Homo sapiens This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
Cellular LocalizationCytoplasmic
Tissue Expression
Signaling_pathway
Research Areas
FunctionTubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
RRID
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