Tubulin γ [PT2188] mouse mAb
Ucallm_WM1278-50
Price range: $268.00 through $328.00
Product details
Background:
tubulin gamma 1(TUBG1) Homo sapiens This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
Specifications
| Size | 50μL/100μL |
| Target | Tubulin γ |
| Reactivity | Human |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 48kD |
| Host Species | Mouse |
| Isotype | IgG2b,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Monoclonal |
| Clone Number | RMM2188 |
| Immunogen | Synthesized peptide derived from human Tubulin γ. AA range: 350-451 |
| Specificity | This antibody detects endogenous levels of Tubulin γ protein. |
| Gene Name | TUBG1 TUBG |
| Protein Name | Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) |
| Other Name | Tubulin gamma-1 chain; / Gamma-1-tubulin; / Gamma-tubulin complex component 1; / GCP-1 |
| Species | Human |
| Gene ID | 7283 |
| Uniprot | P23258;Q9NRH3, |
| Species.1 | Mouse |
| Gene ID.1 | 103733 |
| Uniprot.1 | P83887, |
| Species.2 | Rat |
| Gene ID.2 | 252921 |
| Uniprot.2 | P83888 |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. |
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