Product details
Background:
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],
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TUSC2 Polyclonal Antibody
Ucallm_WP14902-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TUSC2 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 12kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TUSC2. AA range:41-90 |
| Specificity | TUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein. |
| Gene Name | TUSC2 |
| Protein Name | Tumor suppressor candidate 2 |
| Other Name | TUSC2; / C3orf11; / FUS1; / LGCC; / PDAP2; / Tumor suppressor candidate 2; / Fusion 1 protein; / Fus-1 protein; / PDGFA-associated protein 2 |
| Species | Human |
| Gene ID | 11334 |
| Uniprot | O75896, |
| Species.1 | Mouse |
| Gene ID.1 | 80385 |
| Uniprot.1 | Q9WVF8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | mitochondrion, |
| Tissue Expression | Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta., |
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