SKU: WP9016 Categories: ,

TWEAKR/FN14 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP9016-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTNFRSF12A
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)14kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TWEAKR/FN14
SpecificityThis antibody detects endogenous levels of TWEAKR/FN14 at Human, Mouse
Gene NameTNFRSF12A FN14
Protein NameTumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)
Other Name
SpeciesHuman
Gene ID51330
UniprotQ9NP84,
Species.1Mouse
Gene ID.127279
Uniprot.1Q9CR75
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue ExpressionHighly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Signaling_pathwayEnvironmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas
FunctionReceptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
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