TXND2 Polyclonal Antibody
Ucallm_WP2477-50
Price range: $268.00 through $328.00
Product details
Background:
function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase., similarity:Contains 1 thioredoxin domain., subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece., tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids.,
Specifications
| Size | 50μL/100μL |
| Target | TXND2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TXND2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TXNDC2 SPTRX SPTRX1 |
| Protein Name | Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) |
| Other Name | |
| Species | Human |
| Gene ID | 84203 |
| Uniprot | Q86VQ3, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6P902, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5XHX6 |
| Cellular Localization | Cytoplasm . In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece. |
| Tissue Expression | Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.,similarity:Contains 1 thioredoxin domain.,subcellular location:In ejaculated spermatozoa, it localizes in the caudal region of the head to the end of the principal piece.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in round and elongating spermatids., |
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