U-Blot® Acetyl-SOD2 (Lys68) Rabbit mAb
Ucallm_WT9040-100
Price range: $288.00 through $368.00
Product details
Background：
Manganese superoxide dismutase (MnSOD), also named as SOD2, is a mitochondrial detoxification enzyme that catalyzes the conversion of superoxide to hydrogen peroxide. Hydrogen peroxide is then decomposed to water by catalase, glutathione peroxidase, or peroxiredoxins. MnSOD and other enzymes involved in antioxidant defense protect cells from reactive oxygen species (ROS). Calorie restriction leads to SIRT3-mediated deacetylation of MnSOD and the subsequent increase of its antioxidant activity. MnSOD also plays an essential role in mediating the protective effect of mTOR inhibition to reduce epithelial stem cell senescence.
Specifications
| Target | Acetyl-SOD2 (Lys68) |
| Reactivity | Human, Rat, Mouse |
| Application | WB, IHC-P |
| MW(Calculated) | 25 kDa |
| MW(Observed) | 20 kDa |
| Host Species | Rabbit |
| Isotype | IgG/Kappa |
| Conjugate | Unconjugated |
| Modification | Phosphorylation |
| Modified site | Lys68 |
| Recommended dilution ratio | WB: 1:500-1:1000; IHC-P: 1:50-1:100 |
| Composition | PBS, Glycerol, BSA |
| Source | |
| Purification process | Protein A affinity purification |
| Purity | |
| Storage | Store at -20°C. Avoid repeated freeze-thaw cycles |
| Stability | Stable for 12 months from date of receipt / reconstitution. |
| Concentration | |
| Clonality | Recombinant monoclonal |
| Clone Number | W-R79 |
| Immunogen | polypeptide |
| Sequence | |
| Specificity | Specific for SOD2 only when acetylated at Lys68 |
| Gene name | SOD2 |
| Protein Name | Manganese superoxide dismutase (MnSOD) |
| Alternative name | SOD2, Superoxide dismutase |
| Organism-1 | Human |
| Gene ID-1 | 6648 |
| SwissProt-1 | P04179 |
| Organism-2 | |
| Gene ID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| Gene ID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Mitochondrion matrix |
Please login to post questions
Related products
