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Background：c-Kit, also known as CD117, is an important cell surface protein expressed in stem cells and various types of mature cells in humans and other animals. Encoded by the c-Kit gene, the c-Kit protein plays a role in cell proliferation, differentiation, and survival by binding with the cytokine SCF (stem cell factor). Mutations and abnormal expressions of the c-Kit gene have been associated with various diseases including tumors, cardiovascular diseases, and immune system disorders. Research on the c-Kit gene can aid scientists in better understanding its functions in cell biology and pathophysiology, offering new insights for diagnosis and treatment of related diseases.
