Price range: $268.00 through $328.00
Background:The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009],
| Size | 50μL/100μL |
| Target | CD15 |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1606R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | FUT4 |
| Protein Name | Alpha-(1,3)-fucosyltransferase |
| Other Name | FUT4; / ELFT; / FCT3A; / Alpha-; / 1; / 3; / -fucosyltransferase; / ELAM-1 ligand fucosyltransferase; / Fucosyltransferase 4; / Fucosyltransferase IV; / Fuc-TIV; / FucT-IV; / Galactoside 3-L-fucosyltransferase |
| Species | Human |
| Gene ID | 2526 |
| Uniprot | P22083, |
| Species.1 | Mouse |
| Gene ID.1 | 14345 |
| Uniprot.1 | Q11127, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q62994 |
| Cellular Localization | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi. |
| Tissue Expression | [Isoform Short]: Expressed at low levels in bone marrow-derived mesenchymal stem cells.; Expressed in cord blood immature promyelocytes and in peripheral blood myeloid and lymphoid cell populations. |
| Signaling_pathway | |
| Research Areas | >>Mannose type O-glycan biosynthesis; / >>Glycosphingolipid biosynthesis - lacto and neolacto series; / >>Metabolic pathways |
| Function | Caution:It is uncertain whether Met-1 or Met-126 is the initiator.,Function:May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.,online information:Fucosyltransferase 4,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 10 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi., |
