SKU: WR5970 Categories: ,

U-Blot® CD200 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR5970-50
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Product details

Background:
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains , a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types , including B cells , a subset of T cells , thymocytes , endothelial cells , and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq , Jan 2016] ,

Specifications

Size50μL/100μL
TargetCD200
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)31kD
MW(Observed)45-50kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM1879R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameCD200
Protein NameOX-2 membrane glycoprotein
Other NameCD200; / MOX1; / MOX2; / My033; / OX-2 membrane glycoprotein; / CD200
SpeciesHuman
Gene ID4345
UniprotP41217,
Species.1Mouse
Gene ID.1
Uniprot.1O54901,
Species.2Rat
Gene ID.2
Uniprot.2P04218
Cellular LocalizationCell membrane; Single-pass type I membrane protein.
Tissue ExpressionBlood,Brain,Fetal brain,
Signaling_pathway
Research Areas
FunctionFunction:Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD200R1.,
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