Product details
Background:
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains , a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types , including B cells , a subset of T cells , thymocytes , endothelial cells , and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq , Jan 2016] ,






