Name: U-Blot® NDUFA9 Mouse mAb
SKU: WM1830
Price: 268 USD
Availability: InStock

U-Blot® NDUFA9 Mouse mAb

Ucallm_WM1830-50

Price range: $268.00 through $328.00

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50μl

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SKU: WM1830-100

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Product details

Background:This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	NDUFA9
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)	43kD
MW(Observed)	36kD
Host Species	Mouse
Isotype	Mouse IgG1/Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:100-1:200; WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RMMR1441
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	NDUFA9
Protein Name	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 mitochondrial
Other Name	NDUFA9; / NDUFS2L; / NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9; / mitochondrial; / Complex I-39kD; / CI-39kD; / NADH-ubiquinone oxidoreductase 39 kDa subunit
Species	Human
Gene ID	4704
Uniprot	Q16795,
Species.1	Mouse
Gene ID.1	66108
Uniprot.1	Q9DC69,
Species.2	Rat
Gene ID.2	362440
Uniprot.2	Q5BK63
Cellular Localization	Mitochondrion matrix .
Tissue Expression	Blood,Colon,Liver,Muscle,Placenta,Skeletal muscle,
Signaling_pathway	Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas	>>Oxidative phosphorylation; / >>Metabolic pathways; / >>Thermogenesis; / >>Retrograde endocannabinoid signaling; / >>Non-alcoholic fatty liver disease; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Huntington disease; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Chemical carcinogenesis - reactive oxygen species; / >>Diabetic cardiomyopathy
Function	cofactor:Binds 1 FAD per subunit.,Function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA9 subunit family.,subunit:Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.,

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U-Blot® NDUFA9 Mouse mAb

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U-Blot® NDUFA9 Mouse mAb

Product details

Specifications

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