SKU: WM1847 Categories: ,

U-Blot® CD55 Mouse mAb

Price range: $268.00 through $328.00

SKU: WM1847-50
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Product details

Background:
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014],

Specifications

TargetCD55
ReactivityHuman
ApplicationsFC,IF
MW(Calculated)
MW(Observed)
Host SpeciesMouse
IsotypeMouse IgG2a/Kappa
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioIF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
FormulationPBS, pH 7.4
Source
PurificationProtein A
Purity
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
ClonalityMonoclonal
Clone NumberPTF0063
Immunogen
Sequence
SpecificityEndogenous
Gene NameCD55
Protein NameComplement decay-accelerating factor
Other NameCD55;CR;DAF;Complement decay-accelerating factor;CD55
SpeciesHuman
Gene ID-11604
UniprotP08174
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundThis gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014],
Cellular Localization[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .; [Isoform 5]: Secreted .; [Isoform 6]: Cell membrane ; Lipid-anchor, GPI-anchor .; [Isoform 7]: Cell membrane ; Lipid-anchor, GPI-anchor .
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID
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