SKU: WR5714 Categories: ,

U-Blot® CD79b Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR5714-100
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Product details

Background:The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Specifications

TargetCD79b
ReactivityHuman,Mouse,Rat
ApplicationsWB,IHC,IF,IP,ELISA
MW(Calculated)26kD
MW(Observed)32-36kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Modified site
Recommended Dilution RatioIHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification ProcessProtein A
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberPT1518R
Immunogen
Sequence
SpecificityEndogenous
Gene NameCD79B
Protein NameB-cell antigen receptor complex-associated protein beta chain
AliasCD79B;B29;IGB;B-cell antigen receptor complex-associated protein beta chain;B-cell-specific glycoprotein B29;Ig-beta;Immunoglobulin-associated B29 protein;CD79b
Organism-1Human
Gene ID-1974
SwissProt-1P40259
Organism-2Mouse
GeneID-2
SwissProt-2P15530
Organism-3
GeneID-3
SwissProt-3
Organism-4
GeneID-4
SwissProt-4
Cellular LocalizationCell membrane; Single-pass type I membrane protein. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. .
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