SKU: WM1849 Categories: ,

U-Blot® CD94 Mouse mAb

Price range: $268.00 through $328.00

SKU: WM1849-50
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Product details

Background:
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found forThis gene. [provided by RefSeq, Jul 2008]

Specifications

TargetCD94
ReactivityHuman
ApplicationsFC,IF
MW(Calculated)
MW(Observed)
Host SpeciesMouse
IsotypeMouse IgG1/Kappa
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioIF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
FormulationPBS, pH 7.4
Source
PurificationProtein A
Purity
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
ClonalityMonoclonal
Clone NumberPTF0064
Immunogen
Sequence
SpecificityEndogenous
Gene NameKLRD1 CD94
Protein NameNatural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94)
Other NameKLRD1;CD94;Natural killer cells antigen CD94;KP43;Killer cell lectin-like receptor subfamily D member 1;NK cell receptor;CD antigen CD94;CD94 nanobody;
SpeciesHuman
Gene ID-13824
UniprotQ13241
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundNatural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found forThis gene. [provided by RefSeq, Jul 2008]
Cellular LocalizationCell membrane ; Single-pass type II membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
Function
RRID
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