Price range: $268.00 through $328.00
Background:The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014],
| Size | 50μL/100μL |
| Target | ECP |
| Reactivity | Human |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 18kD |
| MW(Observed) | 18kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1652R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | RNASE3 |
| Protein Name | Eosinophil cationic protein |
| Other Name | RNASE3; / ECP; / RNS3; / Eosinophil cationic protein; / ECP; / Ribonuclease 3; / RNase 3 |
| Species | Human |
| Gene ID | 6037 |
| Uniprot | P12724 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted. Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus. |
| Tissue Expression | Colon,Fetal liver,Peripheral blood granulocyte, |
| Signaling_pathway | Human Diseases >> Immune disease >> Asthma |
| Research Areas | >>Asthma |
| Function | Disease:Induces the neurotoxic effect known as the Gordon phenomenon.,Function:Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.,similarity:Belongs to the pancreatic ribonuclease family.,subcellular location:Matrix of eosinophil's large specific granule., |
